
Gut Microbiota-derived Metabolites Regulate Intestinal Motility in Constipation: Mechanisms and Therapeutic Implications
Constipation is a common gastrointestinal disorder characterized by infrequent bowel movements, difficult stool passage, excessive straining, and impaired colonic transit. Increasing evidence indicates that gut microbiota-derived metabolites are active regulators of intestinal motility rather than passive byproducts of luminal fermentation.…







