Nanozymes refer to a class of nanomaterials endowed with enzyme-mimetic catalytic activity. Since the intrinsic peroxidase-like activity of Fe3O4 nanoparticles was discovered by the research group led by Academician Xiyun Yan in 2007, this research field has undergone rapid and vigorous development. This paper systematically reviews the developmental history, classification and catalytic mechanisms of nanozymes. It emphatically elaborates the latest research progress of nanozymes in bioanalytical detection, biomedical applications and environmental pollutant degradation, and prospects the future development directions of nanozymes in the field of bioanalysis. Endowed with the advantages of low cost, high stability, large-scale manufacturability and tunable structural functions, nanozymes demonstrate enormous application potential in biosensing, disease diagnosis and therapy, as well as environmental protection.
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Jiang, Q., Xiao, J., Ling, K., Zhu, H., Wang, G., Li, Y., Yu, P., Wang, Z., Li, B., Zou, S. (2025) Research Progress on the Application of Nanozymes in Biosensors. Scientific Research Bulletin, 2(6), 37-42.